Optimal sequential designs of case-control studies
نویسندگان
چکیده
منابع مشابه
Optimal sequential designs in phase I studies
Phase I clinical trials are conducted in order to find the maximum tolerated dose of a given drug out of a set of doses, usually finite. In general, once a formal target function and a suitable probability structure are defined, optimization of sequential studies can theoretically be achieved using backward induction. This is a computationally heavy task and most of the proposed methods can be ...
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ژورنال
عنوان ژورنال: The Annals of Statistics
سال: 2000
ISSN: 0090-5364
DOI: 10.1214/aos/1015957402